Madhuchhanda Bhattacharjee

Researcher
Division of biometry

Madhuchhanda Bhattacharjee
(Rolf Nevanlinna Institute)
Department of Mathematics and Statistics
Gustaf Hällströmin katu 2b, P.O. Box 68
FIN-00014, University of Helsinki, Finland

Email: mab@rni.helsinki.fi
Phone: +358 9 191 51478
Fax: +358 9 191 51400
Visiting address: Kumpula Campus, Exactum building, room A408

Analytic development for: Modelling and analysis of heterogeneous data, Parametric and Non-Parametric Statistical Inference for Stochastic Processes.

Application areas: Bioinformatics with emphasis to microarray data, Statistical Genetics, Reliability & Survival Analysis, Econometrics.

Theses:


• Ph.D. Thesis: Repairable Systems : Modelling and Some Inference Problems



• M.Phil. Dissertation: Statistical Inference for the Power-Law process : A Model for Repairable Systems



Refereed publications:


• Bayesian Association-Based Fine Mapping in Small Chromosomal Segments, to appear in Genetics, with Mikko J. Sillanpää. (Abstract, Link to Genetics) ( Winbugs code )



• Bayesian Integrated Functional Analysis of Microarray Data (2004), Bioinformatics, Vol. 20, No. 17, pp. 2943-2953, with C.C. Pritchard, P.S. Nelson, E. Arjas. (Abstract, )



• Unconditional Tests of Goodness of Fit for the Intensity of Time-Truncated Nonhomogeneous Poisson Processes (2004), Technometrics, August, Vol. 46, Issue 3, pp. 330-338, with J.V. Deshpande and U.V. Naik-Nimbalkar. (Abstract)



• Modelling heterogeneity: Hierarchical Bayesian approach (2003), in Mathematical Reliability: An Expository Perspective, Ed: Mazzuchi, T.A., Singpurwalla, N.D. and Soyer, R., Kluwer academic publishers, with E. Arjas. (Abstract)



• Bayesian Characterization of Natural Variation in Gene Expression (2003), in Methods of Microarray Data Analysis III, Proceedings of the CAMDA02 Conference, Ed. Johnson K. and Lin, S., Kluwer Academic Publishers, with C.C. Pritchard, M.J. Sillanpää and E. Arjas. (Abstract)



• Bayesian modelling of failure prediction using maintenance information (2003), in Safety and Reliability, Ed. Bedford, T. and van Gelden, P.H.A.J.M., Proceedings of ESREL 2003, A.A.Balkema Publishers/Swets & Zeitlinger, with E. Arjas. (Abstract)



• Bayesian Characterization of Natural Variation in Gene Expression (2002) Abstracts of papers for CAMDA02 Conference, Nov, Durham, USA, with M.J. Sillanpää and E. Arjas.



• Inference for Non-homogeneous Poisson Processes: Models for Repairable Systems, (2001), Proceedings of the International Statistical Institute, August, Seoul, Korea (winning paper of Jan Tinbergen Award 2001). (Abstract)



• Bayesian Nonparametric Estimation of Intensity functions using Markov Chain Monte Carlo Method, (2000), Calcutta Statistical Association Bulletin, 50, pp. 223-235, with J. V. Deshpande and U. V. Naik-Nimbalkar. (Abstract)



• Economic Shocks and Relationship between Relative Price Variability and Inflation Rate in India during 90s, (2000), Indian Journal of Applied Economics, special issue in Honor of Prof. Paul A. Samuelson, 8, Part IV, pp. 357-376, with G. P. Samanta. (Abstract)



• How Useful are Seasonal Adjustment and HP-Filter for Estimating Core Inflation in India? (2000), International Journal of Development Banking, 18, 2, pp. 61-77, with G. P. Samanta. (Abstract)



• Testing of Two Sample Proportional Intensity Assumption for Non-homogeneous Poisson Processes, (1999), Journal of Statistical Planning and Inference, 81, pp. 237-251, with J.V.Deshpande and U.V.Naik-Nimbalkar. (Abstract)



Articles in international compilation works, conference proceedings and presentations:


• Bayesian Latent Class Modelling of Microarray Data (2003), Proceedings of the International Statistical Institute, August, Berlin, Germany, with Elja Arjas. (Abstract)



• Modelling Heterogeneity in Nuclear Power Plant Valve Failure Data (2003), in Mathematical and Statistical Methods in Reliability, Ed. Lindqvist, B. and Doksum, k., World Scientific Publishing Co., with E. Arjas and U. Pulkkinen. (Abstract)



• Bayesian approach to DNA microarray data analysis (2003), in Practical Course on Dna Microarray Technology, Viikki Graduate School in Biosciences, Dec 1-10, University of Helsinki, Finland (invited presentation).



• Bayesian Integrated Functional Analysis of Microarray Data (2003), MIR@W workshop on Bayesian Networks and Microarray analysis, October, Warwick University, UK (invited presentation).



• One step analysis of microarray data, Theme Conference of the Royal Statistical Society, Statistical Genetics and Bioinformatics, July 14-17, Diepenbeck, Belgium.



• Bayesian Integrated Modelling of Gene Expression Data, International Biometric Society, Nordic Regional Conference 2003, June 12- 14, Uppsala, Sweden (invited presentation).



• Bayesian Characterization of Natural Variation in Gene Expression (2002), Critical Assessment of Microarray Data Analysis (CAMDA) Conference, Nov. 14-15, Durham, USA, (invited presentation).



• A unifying approach to analyse microarray based gene expression data (2002), The 3rd Stockholm Workshop in Statistical Genetics, Sept. 12-14, Stockholm, Sweden.



• Modelling Heterogeneity in Nuclear Power Plant Valve Failure Data (2002), Third International Conference on Mathematical Methods in Reliability: Methodology and Practice, June 17-20, Norwegian University of Science and Technology, Trondheim, Norway.



• Bayesian analysis to gene expression data: A case study (2002), Mini-symposium on Computational Biology, June 5, Viikki Biocenter Research Organization, University of Helsinki, Helsinki, Finland (invited presentation).



• Inference for Non-homogeneous Poisson Processes: Models for Repairable Systems, (2001), 53-rd session of the International Statistical Institute, August 22-29, Seoul, South Korea, (invited presentation).



• Inference for Repairable Systems with application to Exchange Rates, (2001), Department of Statistical Mathodology, The Institute of Statistical Mathematics, Tokyo, Japan. (Abstract)



• Tests for Equality of Intensities of Failures of a Repairable System under Two Competing Risks, (2000), Recent Advances in Reliability Theory: Methodology, Practice and Inference, Ed. N. Limnios and M. Nikulin, Birkhäuser Boston, with J.V.Deshpande and U.V.Naik-Nimbalkar. (Abstract)



• Non-Parametric Testing of Intensity Functions of Non-Homogeneous Poisson Processes (1998), SUSAMVAD: The research students’ seminar organised by the University of Pune on the occasion of Golden Jubilee of India’s Independence, Pune, India, (winning paper in the Mathematics, Statistics and Computer Sciences category).



Papers Submitted/ Work in progress:


• Modelling and analysis of time in-homogeneous recurrent event process in heterogeneous population: A case study of HRTs, with Elja Arjas.



• Bayesian characterization of genetic heterogeneity and multilocus association, with Mikko J. Sillanpää.



• The Androgen response program of the developing mouse prostate, with researchers from Fred Hutchinson Cancer Research Centre, USA.



• Inference in hazard regression models under ordering with respect to covariates: A Bayesian perspective, with A. Bhattacharjee, University of Cambridge, UK.



• The molecular program of mouse prostate development: functional analysis with the help of GO, with researchers from Fred Hutchinson Cancer Research Centre, USA.



• To identify and compare concentration dependent effects of TCDD on gene expression in specific human cell lines, with researchers from the National Institute of Environmental Health Sciences, USA.



• Modelling and analysis of bleeding pattern induced by ccHRT, with Elja Arjas.



• Bayesian Latent Class Modelling for Functional Genomics: Combining Experimental Results and Data Base Knowledge (FGBayes). Project under "Systems Biology and Bioinformatics Research Programme (SYSBIO)", funded by Academy of Finland.



Teaching:



Data analysis for gene expression ( Updated course information )